White Paper: Powerful coupling of IC with ICP/MS

Metrohm White Paper WP-008 provides the analytical scientist with a method overview and a collection of applications on the speciation of the most frequently analyzed heavy metals and other substances in matrices ranging from foodstuffs, pharmaceuticals, all kinds of waters to petroleum, soil, and even air samples.

 

Elements: Chromium, Arsenic, Mercury, Iodine, Gadolinium, Selenium, Thallium, Iron, organic compounds, Antimony, Bromate

Online hyphenation of ion chromatography (IC) to inductively coupled plasma mass spectrometry (ICP/MS) is a powerful instrumental tool to handle some of the most challenging analytical tasks. Reliable determination of elemental composition, oxidation states, and chemical binding is crucial to judge toxicity in environmental investigations, water quality control, pharmaceutical and medical analysis, as well as the food and beverage industry.

Coupling of ion chromatography (IC) and inductively-coupled plasma mass spectrometry (ICP/MS)

 

IC-ICP/MS

More than ever do we need to monitor our environment for hazardous substances to protect the basis of our own existence. And more than ever should we insist on a better quality control / process control in the production of our consumer goods such as foodstuffs and pharmaceuticals. One outstanding technique for such controls is the online hyphenation of ion chromatography (IC) to inductively coupled plasma mass spectrometry (ICP/MS). IC-ICP/MS is a powerful instrumental tool to handle some of the most challenging analytical tasks.

ICP/MS can determine the total amount of a specific element in a sample with excellent detection limits (element selectivity). IC copes with species selectivity, i.e., it can separate ionic analytes according to their chemical structure (Herrmann, T.; 2006). The online coupling of IC with ICP/MS thus combines the molecular selectivity of IC with the elemental selectivity and sensitivity of ICP/MS (Knöll, J.; 2013).

As toxicity not only depends on the elemental composition, but also on bioavailability, which is influenced by the oxidation states and chemical binding within the molecule, the reliable determination of these parameters offered by IC-ICP/MS is crucial in environmental investigations, water quality control, pharmaceutical and medical analysis, as well as the food and beverage industry.

Hyphenation of a high-performance IC to an inductively coupled plasma mass spectrometer significantly increases sensitivity while at the same time reducing possible matrix in- terferences to a minimum. IC-ICP/MS is therefore a robust technique for speciation analysis in complex matrices. Some of the most popular applications are shown in this overview.

Norms and standards
More and more norms arise that require the quantification of pollutants like hexavalent chromium or bromate at low concentrations. Table 1 (Download the white paper) lists a few norms and standards that suggest IC-ICP/MS as a test method.

Metrohm has just published a white paper that might be of interest to you:

Coupling of ion chromatography and inductively-coupled plasma mass spectrometry. 

Documents
Questions? Contact us

    Metrohm Australia/New Zealand

    Please select your topic:

    Please select your field of practice:*

    Your message:* (required)

    Please enter

    Your email address*

    Title: MrMrsMsDrProf

    First Name*:

    Last Name*:

    Company/Institution*:

    Address:

    Town:

    State:

    Postcode:

    Country

    Phone Number:

    Would you like to subscribe to one or more of our regular scientific publications?

    Air Water Soil (email)Chemical and Petrochemical Analysis (email)ElectroChem Matters (email)FoodLab and Beverage Analysis (email)Ion Chromatography News (email)Metrohm Australia Analyst (email)Metrohm Australia Analyst (print)Metrohm Information (print)Mines&Minerals (email)Process Analytics (email)Retsch the Sample (print)Solid Science (email)Teaching and Research (email)

    Please enter the displayed code:

    captcha